Author

Edward S. Hems

John Innes CentreORCID 0000-0002-5390-6020Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Barrie M. WilkinsoniD· 2 shared Andrew W. TrumaniD· 1 shared Anne OsbourniD· 1 shared Carlo MartinsiD· 1 shared Christian BassiiD· 1 shared Clare E. M. StevensoniD· 1 shared Daniel C L VaniD· 1 shared Danny VereeckeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

Barrie M. WilkinsonORCID

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3 papers

Recent·Most cited

BiochemistryAngewandte Chemie International EditionPeer-reviewedMay 6, 2026

Discovery and biosynthesis of biffamycin A, a novel glycotetrapeptide antibiotic

Michael W Brigham, Edward S. Hems, Daniel C L Van…·Ryan F. Seipke

The paper discovers and characterizes biffamycin A, a novel glycopeptide antibiotic from Streptomyces albidoflavus, highlighting its antimycobacterial and antistaphylococcal activity.

1 citation

bacteria (other)experimental assay

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Molecular BiologymBioPeer-reviewedAug 7, 2025

Redox control of antibiotic biosynthesis

Rebecca Devine, Katie Noble, Clare E. M. Stevenson…·Matthew I. Hutchings

The paper investigates redox control of antibiotic biosynthesis in Streptomyces formicae, showing that a redox-sensitive repressor senses oxygen to regulate formicamycin production.

7 citations

bacteria (other)experimental assay

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MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedMay 19, 2025

Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target

Jonathan J. Ford, Javier Santos‐Aberturas, Edward S. Hems…·Andrew W. Truman

The paper identifies a biosynthetic gene cluster in Rhodococcus fascians that produces lydiamycin A, a novel HPS-containing macrocyclic pentapeptide with antibacterial activity against peptide deformylase.

10 citationstop 4%

bacteria (other)metagenomics

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