Conditional Dystrophin ablation in the skeletal muscle and brain causes profound effects on muscle function, neurobehavior, and extracellular matrix pathways
Muthukumar Karuppasamy, Katherine G. English, James R. Conner, Shelby N. Rorrer, Michael A. Lopez, David K. Crossman, Jodi R. Paul, Miguel A. Monreal-Gutierrez, Karen L. Gamble, Karyn Ann Esser, Jeffrey J. Widrick, Louis M. Kunkel, Matthew S. Alexander
This study investigates the effects of conditional dystrophin ablation in skeletal muscle and brain, revealing functional deficits and pathway dysregulation in both tissues.
bioRxiv · Jan 30, 2025 · PreprintGenetics