Karen L. Gamble

This study investigates the effects of conditional dystrophin ablation in skeletal muscle and brain, revealing functional deficits and pathway dysregulation in both tissues.

This study investigates how α-synuclein aggregates in the basolateral amygdala affect synaptic structure and function in a mouse model of Parkinson's disease.

This study shows that mouse dentate granule neurons exhibit a 24-hour excitability oscillation regulated by G-protein signaling and Bmal1, affecting memory and spatial discrimination.

This study examines how sex and time-of-day affect hippocampal neurophysiology and spatial memory, finding sex-specific differences in memory performance and synaptic activity across circadian cycles.

This study shows that reducing hypothalamic somatostatinergic neurons in mice leads to diabetes-like symptoms in multiple tissues without hyperglycemia.

This study shows that AD mouse models have impaired clock gene expression and disrupted diurnal regulation of hippocampal inhibitory transmission and spatial memory.