Dhanya K. Cheerambathur

An NADH-controlled gatekeeper of ATP synthase

The paper identifies AIFM1/AK2 interaction as a gatekeeper of mitochondrial ATP synthase, showing it is NADH-dependent and linked to metabolic state, with implications for mitochondrial diseases.

The Kinetochore Protein KNL-1 Regulates the Actin Cytoskeleton to Control Dendrite Branching

This study shows that the kinetochore protein KNL-1 regulates actin dynamics to control dendrite branching in C. elegans neurons.

SID-2 localises to extracellular vesicles in parasitic nematodes and does not function in environmental RNAi

This study identifies SID-2 as an extracellular vesicle protein in parasitic nematodes that does not function in environmental RNAi, suggesting a shift in its ancestral role.

The Outer Kinetochore Proteins KNL-1 and Ndc80 complex are Required to Pattern the Central Nervous System

This study shows that KNL-1 and the NDC-80 complex are essential for proper axonal organization in C. elegans, revealing a non-canonical role for the KMN network in nervous system development.

A toolkit for tissue-specific protein degradation in C. elegans

The paper describes a method for tissue-specific protein degradation in C. elegans using a GFP-targeting nanobody fused to a ubiquitin ligase adaptor, enabling efficient ablation of GFP-tagged proteins in multiple tissues.