Author

William J. Steinbach

University of Arkansas for Medical SciencesORCID 0000-0002-5446-1094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Angela RiveraiD· 1 shared Anna Floyd AveretteiD· 1 shared Eunchong Park· 1 shared Gibeom NamiD· 1 shared Hongjun JangiD· 1 shared Hyunju ParkiD· 1 shared Jen‐Tsan ChiiD· 1 shared Jianli WuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Angela RiveraORCID

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1 paper

Recent·Most cited

Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi

Patrick A. Dome, Pyeonghwa Jeong, Gibeom Nam, Hongjun Jang, Angela Rivera, Anna Floyd Averette, Eunchong Park, Tzu-Chieh Liao, Maria Ciofani, Jianli Wu, Jen‐Tsan Chi, Ronald A. Venters, Hyunju Park, William J. Steinbach, Praveen R. Juvvadi, , Jiyong Hong

This paper designs and synthesizes C22- and C32-modified FK520 analogs with enhanced antifungal activity and reduced immunosuppression by leveraging structural insights from fungal and human CaN-FKBP12 complexes.

Proceedings of the National Academy of Sciences · Dec 31, 2024Peer-reviewedMicrobiology