Philip J. Kingsley

This paper develops COX-2-targeted nanobodies for enhanced endoscopic imaging of colorectal adenomas, showing tumor-specific accumulation in vivo.

The paper investigates how post-transcriptional modifications on tRNA fragments in HDL affect atherosclerosis by altering immune signaling and macrophage activation.

This paper develops micellar nanoparticles that co-deliver a drug and a fluorescent probe for real-time visualization of drug delivery in solid tumors.

This study shows that oncometabolite D-2HG drives enhancer hypermethylation in IDH-mutant gliomas, leading to hyporesponsive microglia and reduced immune reactivity.

This paper shows that Jedi-1-mediated phagocytosis by microglia in the V-SVZ promotes neurogenesis by suppressing inflammatory pathways, and its loss leads to neuroinflammation and reduced neural precursor proliferation.