Author

Annika L. Schroder

Northwestern UniversityORCID 0000-0002-5470-5909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alicia Guemez‐GamboaiD· 2 shared Ximena Gómez-MaqueoiD· 2 shared Ashley Woo· 1 shared Bernie DevliniD· 1 shared Claire M. PhoumyvongiD· 1 shared Clare L Bossert· 1 shared Jennifer RakotomamonjyiD· 1 shared Jordan Gilardi· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Alicia Guemez‐GamboaORCID

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Author profile →

3 papers

Recent·Most cited

Molecular and functional profiling distinguishes PACS1 syndrome variant from PACS1 loss-of-function in iNeurons

Annika L. Schroder, Ximena Gómez-Maqueo, Sean R Golinski, Claire M. Phoumyvong, Richard S. Smith, Alicia Guemez‐Gamboa

The paper compares the molecular and functional effects of a PACS1 variant (p.R203W) with complete PACS1 loss-of-function in iPSC-derived neurons, finding distinct phenotypes suggesting a non-loss-of-function mechanism.

bioRxiv · Sep 1, 2026 · PreprintNeuroscience

Filopodia numbers impact chemotactic migration speed

Annika L. Schroder, Livia D. Songster, Yahor Savich, Margaret A. Titus

This study shows that filopodia number affects chemotactic migration speed in Dictyostelium amoebae, but not directional persistence, suggesting a role in tuning cell-substrate adhesion.

bioRxiv · May 28, 2025 · PreprintCell Biology

PACS1 syndrome variant alters proteomic landscape of developing cortical organoids

Ximena Gómez-Maqueo, Lauren E. Rylaarsdam, Ashley Woo, Annika L. Schroder, Jennifer Rakotomamonjy, Clare L Bossert, Tess A Smith, Shelby Ruiz, Jordan Gilardi, Lambertus Klei, Bernie Devlin, Matthew L. MacDonald, Alicia Guemez‐Gamboa

This study examines how the PACS1 p.R203W variant affects the proteomic landscape of brain organoids, identifying dysregulated proteins and processes linked to neurodevelopmental disorders.

bioRxiv · Apr 23, 2025 · PreprintNeuroscience