Michael W. Chevalier

The paper develops a synapse-based ODE model for immune cell engagers that shows trimer per synapse invariance across effector-to-tumor ratios, improving mechanistic understanding of bispecific antibody function.

The paper introduces CLASP, an optogenetic tool to control TF localization, and shows differential promoter responses to pulsatile vs. continuous TF inputs.

This paper designs and analyzes a biochemical PID controller using biological molecules, showing improved performance through computational and analytical methods.