Keren Lasker

nELAVL phosphorylation by CDKL5 regulates RNA metabolism and condensates communication to promote experience-dependent maturation of the visual cortex

This study identifies CDKL5-mediated phosphorylation of nELAVL as critical for regulating RNA metabolism and condensate communication, essential for visual cortex maturation.

Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure

The paper investigates how the ultrastructure of biomolecular condensates, using PopZ as a model, influences their function through molecular interactions and phase-dependent conformational changes.

Biomolecular Condensates can Induce Local Membrane Potentials

The paper shows that biomolecular condensates can induce local membrane potentials in Giant Unilamellar Vesicles, with effects influenced by salt concentration and ATP-to-poly-lysine ratios.

Generative modeling of short, disordered proteins with homogeneous sequence composition

This paper develops a generative model for short, disordered proteins by learning the distribution of ensemble-averaged pairwise distance maps from coarse-grained simulations.