Author

Alexandra Salazar

Howard Hughes Medical InstituteORCID 0000-0002-6428-9398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Adrienne E. DubiniD· 1 shared Alex S. HolehouseiD· 1 shared Alexander Theodore ChesleriD· 1 shared Andrej ŠaliiD· 1 shared Andrew P. LathamiD· 1 shared Ardem PatapoutianiD· 1 shared Ashok A. DeniziD· 1 shared Asma M. A. M. Khan· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adrienne E. DubinORCID

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2 papers

Recent·Most cited

Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure

Daniel Scholl, Tumara Boyd, Andrew P. Latham, Alexandra Salazar, Asma M. A. M. Khan, Steven Boeynaems, Alex S. Holehouse, Gabriel C. Lander, Andrej Šali, Donghyun Park, Ashok A. Deniz, Keren Lasker

The paper investigates how the ultrastructure of biomolecular condensates, using PopZ as a model, influences their function through molecular interactions and phase-dependent conformational changes.

Nature Structural & Molecular Biology · Feb 2, 2026Peer-reviewedCell Biology

Excessive Mechanotransduction in Sensory Neurons Causes Joint Contractures in a Mouse Model of Arthrogryposis

Shang Ma, Adrienne E. Dubin, Luis O. Romero, Meaghan C. Loud, Alexandra Salazar, Yu Wang, Alexander Theodore Chesler, Katherine A. Wilkinson, Valeria Vásquez, Kara L. Marshall, Ardem Patapoutian

The paper shows that a gain-of-function PIEZO2 mutation in sensory neurons causes joint contractures in mice, and that Botox and dietary fatty acids can alleviate these defects.

bioRxiv · Jun 7, 2022 · PreprintNeuroscience