Author

M J Lee

Georgetown UniversityORCID 0000-0002-5484-3383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anna M. JermakowicziD· 1 shared Daniel T. WynniD· 1 shared David J. RobbinsiD· 1 shared Erik T. Goka· 1 shared Isabelle EganiD· 1 shared Jonathan ChuiD· 1 shared Luz Clarita RuiziD· 1 shared M. E. Lippman· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anna M. JermakowiczORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNeuro-OncologyPeer-reviewedMar 19, 2026

RAC1 Regulates Shh-Medulloblastoma Growth via GLI-Mediated Transcription

Nitish Jangde, M J Lee, Luz Clarita Ruiz…·Nagi G. Ayad

This study identifies RAC1 as a druggable target in Shh-dependent medulloblastoma by showing its role in regulating GLI1 and GLI2 transcription and demonstrating the efficacy of the inhibitor GYS32661 in reducing tumor growth.

DOI 10.1093/neuonc/noag057

mouseexperimental assay

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