Spared Nav1.8-Positive Nociceptors Drive Persistent Tactile Hypersensitivity After Sciatic Nerve Crush Injury in Mice
Sang Wook Shim, Yoon Kyung Lee, Dahee Roh, Kihwan Lee, Hyoung Woo Kim, Seog Bae Oh
Pain · Jan 15, 2026Peer-reviewedNeuroscience
Author
Hyoung Woo Kim
Boston Children's HospitalORCID 0000-0002-5487-0146Unclaimed ORCID profile · follow to get notified of new preprints
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2025-2026 · peak 2/yrCo-Author Collaboration Network
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Recent·Most cited
Peripheral Nerve Transection Predominantly Drives Sympathetic Nerve Sprouting in Mouse Dorsal Root Ganglia
Sang Wook Shim, Hyoung Woo Kim, Yoon Kyung Lee, Clifford J. Woolf, Kihwan Lee, Seog Bae Oh
This study compares nerve transection and crush injury models to show that transection drives sympathetic sprouting and pain, while crush injury causes pain through non-sympathetic mechanisms.
Pain · Jan 15, 2026Peer-reviewedNeuroscience
Lipid nanoparticle delivery of siRNA to dorsal root ganglion neurons to treat pain
Xiangfei Han, Veselina Petrova, Yudong Song, Yu‐Ting Cheng, Xingya Jiang, Hui Hua Zhou, Caleb Hu, Dean Shuailin Chen, Hyo Jeong Yong, Hyoung Woo Kim, Biyao Zhang, Omer Barkai, Aakanksha Jain, William R. Renthal, Philipp B. Lirk, , Jinjun Shi
This study demonstrates the use of lipid nanoparticles to deliver siRNA to dorsal root ganglion neurons, effectively silencing TRPV1 and reducing pain-related behaviors.
bioRxiv · Jan 23, 2025 · PreprintNeuroscience