Spared Nav1.8-Positive Nociceptors Drive Persistent Tactile Hypersensitivity After Sciatic Nerve Crush Injury in Mice
Sang Wook Shim, Yoon Kyung Lee, Dahee Roh, Kihwan Lee, Hyoung Woo Kim, Seog Bae Oh
Pain · Jan 15, 2026Peer-reviewedNeuroscience
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Seoul National UniversityORCID 0000-0001-7975-6895Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Sang Wook Shim, Yoon Kyung Lee, Dahee Roh, Kihwan Lee, Hyoung Woo Kim, Seog Bae Oh
Pain · Jan 15, 2026Peer-reviewedNeuroscience
Sang Wook Shim, Hyoung Woo Kim, Yoon Kyung Lee, Clifford J. Woolf, Kihwan Lee, Seog Bae Oh
This study compares nerve transection and crush injury models to show that transection drives sympathetic sprouting and pain, while crush injury causes pain through non-sympathetic mechanisms.
Pain · Jan 15, 2026Peer-reviewedNeuroscience
Shuaiwei Wang, Allison M Barry, Yoon Kyung Lee, Naomi Young, Sang Wook Shim, Xinying Wang, Hyeongcheol Kim, Laura Stirling-Barros, Rafael González‐Cano, Michael Costigan, Georgios Baskozos, Simon Rinaldi, David Bennett, Seog Bae Oh, Alexander J. Davies
Journal of Neuroinflammation · Dec 29, 2025Peer-reviewedNeuroscience
Hayun Kim, Yoon Kyung Lee, Seog Bae Oh
The paper identifies cold-responsive neurons in the lateral parabrachial nucleus that mediate cold-induced analgesia via enkephalin release in the ventrolateral periaqueductal gray.
bioRxiv · Nov 10, 2025 · PreprintNeuroscience
Hiroki Toyoda, Doyun Kim, Byeong Geon Koh, Tomomi Sano, Takashi Kanematsu, Seog Bae Oh, Youngnam Kang
This study shows chronic stress reduces 2A-AR and GIRK currents in locus coeruleus neurons, leading to increased NA-autocrine and AEP activity.
bioRxiv · Mar 10, 2025Neuroscience