Author

Hyeon‐Cheol Lee

Juntendo UniversityORCID 0000-0002-5493-8112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Takehiko YokomizoiD· 4 shared Akari HagiwaraiD· 1 shared Akira Katayanagi· 1 shared Aran Groves· 1 shared Arjun SahaiD· 1 shared Atsushi HashizumeiD· 1 shared Chihana Kabuta· 1 shared Clayton Ellington· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersNeuroscience

Takehiko YokomizoORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 18, 2026

PLCXD2 preferentially hydrolyzes phosphatidylinositol and supports retinal lipid homeostasis and photoreceptor integrity

Kaori Kanemaru, Wako Iwata, Akira Katayanagi…·Yoshikazu Nakamura

This study identifies PLCXD2 as a phosphatidylinositol-preferring phospholipase that maintains retinal lipid homeostasis and photoreceptor integrity.

DOI 10.64898/2026.09.13.750855

mouseexperimental assay

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Cell BiologyCell ReportsPeer-reviewedJun 1, 2025

The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders

Ryohei Sakai, Shu Aizawa, Hyeon‐Cheol Lee…·Tomohiro Kabuta

This study identifies LAMP2B as a mediator of microlipophagy, showing its role in preventing obesity and related metabolic disorders through enhanced lipid hydrolysis.

17 citationstop 3%

mousemetabolomics

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NeurosciencebioRxivPreprintJan 12, 2024

Dysregulated expanded endocannabinoid system as therapeutic targets of amyotrophic lateral sclerosis

Daisuke Ito, Madoka Iida, Yohei Iguchi…·Masahisa Katsuno

The paper identifies dysregulated expanded endocannabinoid system metabolites in ALS and shows FAAH inhibition improves motor neuron degeneration in models.

2 citations

humanmetabolomics

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NeuroscienceCell ReportsPeer-reviewedDec 1, 2023

FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis

Deepa Jonnalagadda, Yasuyuki Kihara, Aran Groves…·Jerold J. M. Chun

The paper identifies a mechanism by which FTY720 reduces MS-like disease in an animal model through B12-TCN2-CD320 signaling in astrocytes.

17 citations

mousebulk RNA-seq

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