Developmental BiologyCellPeer-reviewed
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
Alex A. Pollen, Aparna Bhaduri, Madeline G. Andrews…·Arnold R. Kriegstein
The paper uses chimpanzee cerebral organoids to identify human-specific genes in cortical development and finds increased PI3K/AKT/mTOR activation in human outer radial glia.
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