Adam J. M. Wollman

MaCADEMIA is a MATLAB toolbox for single-molecule fluorescence image analysis, providing accurate quantification of molecular properties in living cells.

The paper investigates the molecular architecture of the Fps1 aquaglyceroporin gating system in yeast, revealing that Rgc2 functions as a homodimer and Rgc1 influences its dynamics and stability.

Flight-Scope enables live-cell imaging of dynamic processes in microgravity using microfluidics during parabolic flights, demonstrated with yeast glucose uptake.

The paper compares the behavior of Hsp104 fluorescent fusions in yeast, finding that fluorescent tags and fluorophores can alter molecular behavior in protein quality control and aging research.

The paper uses single-molecule fluorescence microscopy to study SpoIIE dynamics in Bacillus subtilis during sporulation, revealing changes in stoichiometry and mobility that enable stage-specific functions.

This study uses single-molecule tracking to show EGFR homoclusters pre-activate and form heteroclusters with HER2 after EGF binding, with a peak EGFR-to-EGF ratio of 2.

The paper develops a super-resolution microscopy system for rapid molecular tracking in live tissues and demonstrates its application to chemokine molecules in collagen and lymph node tissues.