Hippocampal sharp wave ripples mediate generalization and subsequent fear attenuation via closed-loop brain stimulation in rats
Lizeth Katherine Pedraza, Rodrigo O. Sierra, Lívia Barcsai, Qun Li, Andrea Pejin, Levente Gellért, Magor L. Lörincz, Antal Berényi
This study shows that closed-loop brain stimulation targeting the amygdala or prefrontal cortex after fear memory reconsolidation reduces fear generalization and enhances extinction in rats.
bioRxiv · Apr 30, 2024 · PreprintNeuroscience