Lívia Barcsai

Phase-dependent closed-loop intersectional short-pulse stimulation reduces seizure duration: From computational modeling to clinical application

This study shows that phase-targeted intersectional short-pulse stimulation reduces seizure duration in both rat models and human patients.

Non-vectorial Integration of Intersectional Short-Pulse Stimulation Enables Enhanced Deep Brain Modulation and Effective Seizure Control

This paper demonstrates that Intersectional Short-Pulse (ISP) stimulation improves seizure control in a rat model of temporal lobe epilepsy compared to conventional TES.

Hippocampal sharp wave ripples mediate generalization and subsequent fear attenuation via closed-loop brain stimulation in rats

This study shows that closed-loop brain stimulation targeting the amygdala or prefrontal cortex after fear memory reconsolidation reduces fear generalization and enhances extinction in rats.

Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges in absence seizures

This study investigates how higher-order thalamic nuclei contribute to the spread and maintenance of spike-and-wave discharges in absence seizures using GAERS models.

Closed-loop brain stimulation to reduce pathologic fear

This study shows that closed-loop brain stimulation using hippocampal sharp wave-ripples can enhance fear extinction memory consolidation and reduce pathologic fear in a PTSD model.

Reinstating olfactory bulb derived limbic gamma oscillations alleviates depression

The paper shows that restoring gamma oscillations in the limbic system via olfactory bulb neuromodulation alleviates depressive-like behaviors in animals.