Jasper J. Michels

This paper introduces programmable DNA-based protonuclei to study protein phase separation, showing that environmental factors significantly influence FUS behavior.

The paper develops a thermodynamic model that unifies phase separation and β-sheet-based aging in intrinsically disordered proteins, validated using nucleoporin-98 variants.

This study investigates whether mechanical forces during collective epithelial migration can trigger cytoplasmic liquid-liquid phase separation, showing feedback effects on motility.

The paper identifies preprocessing bias in chromatin contact data and introduces a framework to correct it, enabling physically interpretable genome architecture reconstruction.

This study shows that PEG affects phase-separated droplets differently depending on the protein, accelerating Nup98 maturation but stabilizing BSA droplets.

This study investigates RNA polymerase II condensates in C. elegans using simulations and experiments, showing they exhibit LCST behavior and form distinct phases during transcription.