GeneticsbioRxivPreprint
The first transchromosomic rat model with human chromosome 21 shows robust Down syndrome features
Yasuhiro Kazuki, Feng Gao, Miho Yoshida Yamakawa…·Roger H. Reeves
The paper develops a transchromosomic rat model with human chromosome 21 that exhibits key Down syndrome features and provides a tool for DS research and drug development.
DOI 10.1101/2021.10.03.462958