Alicia E. Tanneberger

Hydrogel-Embedded Precision-Cut Lung Slices Recapitulate Fibrotic Gene Expression and Enable Therapeutic Response Evaluation

This paper develops a hydrogel-embedded PCLS model to study pulmonary fibrosis, showing prolonged viability and matching fibrotic gene expression patterns in human tissue.

Female fibroblast activation is estrogen-mediated in sex-specific 3D-bioprinted pulmonary artery adventitia models

This paper develops a 3D-bioprinted model of pulmonary artery adventitia using female patient-derived cells to show that estrogen signaling mediates fibroblast activation in PAH, with implications for drug testing.

Biomaterial-based 3D human lung models replicate pathological characteristics of early pulmonary fibrosis

This paper develops 3D human lung models using biomaterials to replicate early pulmonary fibrosis features and tests drug responses.

Engineered hydrogel biomaterials facilitate lung progenitor cell differentiation from induced pluripotent stem cells

This study shows engineered hydrogels improve lung progenitor cell differentiation from iPSCs compared to Matrigel, offering a more defined and controllable method for clinical applications.