Author

Xi Xiang

BGI Group (China)ORCID 0000-0002-5590-7289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Xiuqing ZhangiD· 3 shared Yonglun LuoiD· 3 shared George McDonald ChurchiD· 2 shared Huanming YangiD· 2 shared Jun WangiD· 2 shared Lars BolundiD· 2 shared Lin LiniD· 2 shared Xin LiuiD· 2 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersSystems Biology

Xiuqing ZhangORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintMay 20, 2020

Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

Xi Xiang, Kunli Qu, Xue Liang…·Yonglun Luo

The paper introduces TRAP-seq to quantify CRISPR editing efficiency and uses it to design improved gRNAs for Cas9, ABE, and CBE with high accuracy and efficiency.

3 citations

humanCRISPR screen

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 11, 2019

CRISPR-GNL: an improved model for predicting CRISPR activity by machine learning and featurization

Jun Wang, Xi Xiang, Lixin Cheng…·Yonglun Luo

The paper develops a CRISPR on-target activity prediction model called GNL using Bayesian Ridge Regression, showing improved cross-dataset and cross-species performance.

15 citations

CRISPR screenBayesian inference

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GenomicsNucleic Acids ResearchPeer-reviewedAug 22, 2018

Circularization of genes and chromosome by CRISPR in human cells

Henrik Devitt Møller, Lin Lin, Xi Xiang…·Yonglun Luo

This study demonstrates CRISPR/Cas9 can generate extrachromosomal circular DNA and ring chromosomes in human cells, enabling new tools for genetic engineering and disease modeling.

117 citationstop 4%

humanexperimental assay

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