BiochemistryJournal of Lipid ResearchPeer-reviewed
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling
Adolf Koudelka, Gregory J. Buchan, Veronika Cechova…·Stacy L. Gelhaus
This paper shows that LXA4 and its 15-oxo metabolite do not activate FPR2 receptor but instead modulate redox-sensitive pathways through electrophilic interactions.
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