Author

Yukitoshi Izumi

Washington University in St. LouisORCID 0000-0002-5596-1031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:electronic health records· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Charles F. ZorumskiiD· 3 shared Steven J. MennerickiD· 3 shared Alexis N. Harris· 1 shared Andrew D. SauerbeckiD· 1 shared Angela Michelle ReierseniD· 1 shared Christopher Trousdale· 1 shared Douglas F. CoveyiD· 1 shared Elliot C. NelsoniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Charles F. ZorumskiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 24, 2025

VDAC activation inhibits hippocampal plasticity via NLRP3 inflammasome & caspase-1: modulation by allopregnanolone enantiomers

Yukitoshi Izumi, K. M. C. O'Dell, Douglas F. Covey…·Charles F. Zorumski

This study shows that VDAC activation by erastin inhibits hippocampal long-term potentiation and memory formation, effects that are prevented by allopregnanolone and its enantiomer.

DOI 10.1101/2025.10.24.684242

ratelectronic health records

𝕏 PostBluesky

NeuroscienceTranslational PsychiatryPeer-reviewedNov 21, 2024

Sertraline modulates hippocampal plasticity and learning via sigma 1 receptors, cellular stress and neurosteroids

Yukitoshi Izumi, Angela Michelle Reiersen, Eric J. Lenze…·Charles F. Zorumski

This study investigates how sertraline affects hippocampal plasticity and learning through sigma 1 receptors, cellular stress, and neurosteroids in rat models.

14 citations

ratelectronic health records

𝕏 PostBluesky

NeuroscienceBiological PsychiatryPeer-reviewedJul 23, 2021

Cornichon Homolog-3 (CNIH3) Modulates Spatial Memory in Female Mice

Hannah E. Frye, Yukitoshi Izumi, Alexis N. Harris…·José A. Morón

This study investigates the role of CNIH3 in spatial memory, finding sex-specific effects where CNIH3 deficiency impairs spatial memory in female mice but not males.

20 citations

mouseexperimental assay

𝕏 PostBluesky