San Hadži

This paper shows how ionic strength affects the structural disorder and oligomerization of the Phd transcription factor, revealing its ability to function as a conformational rheostat.

ChiraKit is an online tool that processes and analyzes circular dichroism data to calculate secondary structure, estimate helicity, fit unfolding models, and decompose spectra.

The paper investigates factors stabilizing pre-folded helical structures in intrinsically disordered proteins and finds that leucine residues contribute significantly to this stabilization.