Author
Guangzhou Regenerative Medicine and Health Guangdong LaboratoryORCID 0000-0002-5640-1896Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jin-Hui Ding, Jiale Wang, Weifeng Zhang…·Jin‐Peng Sun
This paper reveals how mechanical force activates mGlu2 through a unique cis mechanism and induces distinct Gq coupling, providing structural insights and a chemical toolset for modulating mechanosensitive GPCRs.
Yujia Huo, Yiwei Zhou, Lin Li…·Jianfeng Liu
This paper shows that GABAB receptors can be activated by mechanical forces without GABA, through integrin-GB1 interactions leading to receptor activation and astrocyte remodeling.
Chunyou Mao, Cangsong Shen, Chuntao Li…·Yan Zhang
The paper presents cryo-EM structures of the GABAB receptor in inactive and active states, revealing structural changes and Gi1 coupling mechanisms.