NeurosciencebioRxivPreprint
Type I PRMT inhibitor MS023 promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue the phenotype of SMA mice
Anna J. Kordala, Nina Ahlskog, Muhammad Hanifi…·Carlo Rinaldi
1 citation
Author
Suzan M. Hammond
John Radcliffe HospitalORCID 0000-0002-5640-7569Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2022 · peak 1/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Molecular BiologybioRxivPreprint
Systemic antibody-oligonucleotide delivery to the central nervous system ameliorates mouse models of spinal muscular atrophy
Suzan M. Hammond, Frank Abendroth, Larissa Goli…·Carl I. Webster
This study demonstrates that systemic delivery of ASO conjugated to a brain-targeting antibody improves SMN2 splicing and survival in SMA mouse models.
10 citations - NeurosciencebioRxivPreprint
Combining multi-omics and drug perturbation profiles to identify novel treatments that improve disease phenotypes in spinal muscular atrophy
Katharina E. Meijboom, Viola Volpato, Jimena Monzón‐Sandoval…·Mélissa Bowerman
This study identifies novel drug treatments for spinal muscular atrophy by integrating multi-omics data and drug perturbation profiles, showing harmine improves disease phenotypes in models.
1 citation