Laure Menin

De novo design of light-controlled conformational protein switches

This paper computationally designs light-responsive proteins that undergo conformational changes upon light activation, enabling precise control of biological functions.

Computational design of microbial and animal rhodopsin soluble analogues

This study computationally designs soluble analogues of animal and microbial rhodopsins, showing they are well-folded, thermostable, and retain retinal photocycle functionality.

Redox-regulated cysteine acylation governs β-lactam sensing by the Vibrio histidine kinase VbrK

This study reveals how β-lactam antibiotics interact with the histidine kinase VbrK through redox-dependent cysteine acylation, enabling bacterial resistance.

On demand nanoliter sampling probe for collection of brain fluid

This paper introduces a new microfabricated neural probe that enables precise, transient-free sampling of brain extracellular fluid biomarkers in vivo and in vitro.