Jim Lagopoulos

Resting-State EEG Aperiodic Exponent Moderates the Association Between Age and Memory Performance in Older Adults

This study finds that the aperiodic exponent in resting-state EEG moderates age-related memory decline in older adults, with higher exponents associated with better memory performance.

Temporal Immune Effects of Oral Ketamine on PTSD: Transcriptomic Evidence of Short-Term Inflammation Suppression and Long-Term Immune Remodelling

This study examines the short- and long-term transcriptomic effects of oral ketamine on PTSD, revealing inflammation suppression and immune remodelling through gene expression analysis.

Methylome and transcriptome functional analysis identifies key biomarkers in ketamine's sustained therapeutic effect on PTSD

This study identifies key methylomic and transcriptomic biomarkers predictive of sustained ketamine response in PTSD by comparing responders and non-responders.

Brain-Age Prediction: Systematic Evaluation of Site Effects, and Sample Age Range and Size

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

EEG-based clusters differentiate psychological distress, sleep quality and cognitive function in adolescents

The paper identifies EEG-based clusters in adolescents that correlate with psychological distress, sleep quality, and cognitive function using clustering and Bayesian regression.

Elucidating the neuroanatomical correlates of social connectedness, sleep quality and psychological distress in early adolescence

The paper examines the relationship between social connectedness, sleep quality, white matter integrity, and psychological distress in early adolescents using regression analysis.

Greater male than female variability in regional brain structure across the lifespan

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

This paper examines brain aging in major depressive disorder (MDD) using a large dataset, finding that MDD patients show increased brain age differences compared to controls.

Altered White Matter Microstructural Organization in Post-Traumatic Stress Disorder across 3,049 Adults: Results from the PGC-ENIGMA PTSD Consortium

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.