Xavier Caseras

A Scalable Toolkit for Modeling 3D Surface-based Brain Geometry

The paper introduces a scalable toolkit for 3D surface-based brain analysis, demonstrating its utility in mapping subcortical shape variations across 21 international samples.

Brain-Age Prediction: Systematic Evaluation of Site Effects, and Sample Age Range and Size

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

The impact of genetic risk for Alzheimers disease on the structural brain networks of young adults

This study examines how genetic risk for Alzheimer's disease affects structural brain networks in young adults using MRI and genotype data.

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

The paper examines age-related variations in cortical thickness across different life stages using gene expression data from a large neuroimaging dataset.

Analysis of diffusion tensor imaging data from UK Biobank confirms dosage effect of 15q11.2 copy-number variation on white matter and shows association with cognition

The paper analyzes diffusion tensor imaging data from UK Biobank to show that 15q11.2 copy-number variation affects white matter and is associated with cognitive performance.

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

The paper analyzes cortical thickness trajectories in 17,075 individuals to show peak thickness in childhood, steep decline in early adulthood, and slower decline later, with notable exceptions and significant inter-individual variability.

Identifying genetic variants associated with cerebellar volume in 33,265 individuals from the UK-Biobank

This study identifies 33 genome-wide significant SNPs associated with cerebellar volume in 33,265 UK-Biobank participants, highlighting 21 candidate genes and genetic correlations with other brain structures.

Greater male than female variability in regional brain structure across the lifespan

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

This paper examines brain aging in major depressive disorder (MDD) using a large dataset, finding that MDD patients show increased brain age differences compared to controls.

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

This study analyzes subcortical volume changes across the lifespan using MRI data from 18,605 individuals, finding age-related declines in some structures and increases in others.

Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank

The paper examines subcortical brain volume differences between schizophrenia-associated CNV carriers and non-carriers in UK Biobank, finding reduced volumes in some structures and partial mediation by cognitive impairment.