Author

Yuping A. Cai

Chinese Academy of SciencesORCID 0000-0002-5701-3609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Zheng‐Jiang ZhuiD· 3 shared Nan LiuiD· 2 shared Yandong YiniD· 2 shared Zaijun MaiD· 2 shared Feng LiuiD· 1 shared Han WangiD· 1 shared Haosong ZhangiD· 1 shared Huanhuan MaiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioinformatics

Zheng‐Jiang ZhuORCID

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3 papers

Recent·Most cited

Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic network

Zhiwei Zhou, Mingdu Luo, Haosong Zhang, Yandong Yin, Yuping A. Cai, Zheng‐Jiang Zhu

This paper introduces KGMN, a method for annotating unknown metabolites in untargeted metabolomics by integrating multiple networks, and validates several unknowns through computational and experimental approaches.

bioRxiv · Jun 2, 2022 · PreprintBioinformatics

Metabolic Reaction Network-based Recursive Metabolite Identification for Untargeted Metabolomics

Xiaotao Shen, Ruohong Wang, Xin Xiong, Yandong Yin, Yuping A. Cai, Zaijun Ma, Nan Liu, Zheng‐Jiang Zhu

The paper introduces a recursive algorithm and webserver, MetDNA, for large-scale and unambiguous metabolite identification in untargeted metabolomics.

Nature Communications · Apr 3, 2019Peer-reviewedBioinformatics

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

Zaijun Ma, Hui Wang, Yuping A. Cai, Han Wang, Kongyan Niu, Xiaofen Wu, Huanhuan Ma, Yun Yang, Wenhua Tong, Feng Liu, Zhandong Liu, Yaoyang Zhang, Rui Liu, Zheng‐Jiang Zhu, Nan Liu

This study shows that aging causes H3K27me3 drift, reducing glycolytic gene expression and lifespan, while PRCs-deficiency or glycolytic gene increase improves longevity.

eLife · May 29, 2018Peer-reviewedMolecular Biology