Zheng‐Jiang Zhu

CRISPR screens reveal ZBTB17/MIZ1 as a peroxisome regulator

This study identifies ZBTB17/MIZ1 as a peroxisome regulator through CRISPR screens, showing its role in protein import and metabolic regulation.

Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic network

This paper introduces KGMN, a method for annotating unknown metabolites in untargeted metabolomics by integrating multiple networks, and validates several unknowns through computational and experimental approaches.

metID: A R package for automatable compound annotation for LC-MS-based data

metID automates compound annotation for LC-MS data by integrating multiple databases, improving efficiency and reproducibility.

MS-DIAL 4: accelerating lipidomics using an MS/MS, CCS, and retention time atlas

MS-DIAL 4 provides a comprehensive lipidome atlas with retention time, collision cross section, and MS/MS data to standardize and accelerate lipidomics research.

Metabolic Reaction Network-based Recursive Metabolite Identification for Untargeted Metabolomics

The paper introduces a recursive algorithm and webserver, MetDNA, for large-scale and unambiguous metabolite identification in untargeted metabolomics.

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

This study shows that aging causes H3K27me3 drift, reducing glycolytic gene expression and lifespan, while PRCs-deficiency or glycolytic gene increase improves longevity.