Feng Liu

This study identifies METTL1 O-GlcNAcylation and ubiquitination as key regulators of m7G modification and lipid metabolism in diabetic cardiomyopathy, with a drug targeting this pathway showing therapeutic potential.

This study profiles CD8+ T cells in AxSpA synovium using scRNA-seq, identifying HLA-DR+ TRM and KIR+ subsets with distinct transcriptional features and potential pathogenic roles.

The paper shows that global DNA methylation inheritance and enhancer dememorization in zebrafish embryos protect embryonic gene programs by preventing ectopic gene activation.

This study shows that Smarca5 regulates erythrocyte aggregation through Keap1-Nrf2 signaling in zebrafish, leading to venous thrombosis-like phenotypes.

This study shows that aging causes H3K27me3 drift, reducing glycolytic gene expression and lifespan, while PRCs-deficiency or glycolytic gene increase improves longevity.