Andrew Flaus

This study identifies AEBP2 as a therapeutic target in EZH2-mutant lymphoma by showing its role in maintaining H3K27me2 levels through a PRC2.2 complex.

This study characterizes enolase from Fasciola hepatica as a moonlighting protein that binds host extracellular matrix and fibrinolytic components, aiding parasite invasion and migration.

The paper shows that spH2B variants in Hydractinia sperm stabilize chromatin and block transcription without significantly compacting chromatin, supporting their role in sperm buoyancy.

The paper examines the association between genomic instability, measured by copy number alterations, and survival outcomes in luminal breast cancers, finding that higher CNA burden correlates with poorer survival in luminal A grade 3 tumors.

The paper catalogs the human canonical core histone genes and proteins, revealing extensive isoform diversity and updating annotations based on genome data.