Barbara Imperiali

The paper identifies the final N-linked glycan structure in Campylobacter concisus and reveals the roles of two glycosyltransferases in its diversification.

This paper introduces a detergent exchange method to transfer membrane proteins from lipid nanoparticles to detergent micelles, preserving function and homogeneity for biochemical analysis.

The paper integrates bioinformatics, molecular dynamics, and single-molecule FRET to study ligand-dependent conformational dynamics of membrane proteins.

This paper develops a method to select nanobodies against membrane proteins embedded in liponanoparticles using yeast surface display, achieving high-affinity and stable Nb-protein complexes.

The paper introduces glycan analysis probes (GAPs) inspired by human lectins to study host-microbe interactions and glycan-mediated processes.

The paper identifies and validates substrate specificity of bacterial monotopic phosphoglycosyl transferases using bioinformatics and in vitro assays, supporting inhibitor discovery for antibiotic development.