ImmunologybioRxivPreprint
Steady-state phosphorylation of SHIP1 by Lyn restricts macrophage activation in the absence of a phagocytic synapse
S. Erandika Senevirathne, William K. Kanagy, Richard T. Cattley…·Tanya S. Freedman
The paper shows that Lyn maintains steady-state phosphorylation of SHIP1, balancing Erk and Akt signaling in macrophages, and that phagocytic synapse formation bypasses this requirement.
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