Author

S. Erandika Senevirathne

University of MinnesotaORCID 0000-0001-9637-440XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Silvia Toledo RamosiD· 2 shared Tanya S. FreedmaniD· 2 shared Carter SellneriD· 1 shared Myra G. NuneziD· 1 shared Richard T. CattleyiD· 1 shared Whitney L. SwansoniD· 1 shared William F. HawseiD· 1 shared William K. KanagyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Silvia Toledo RamosORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 27, 2026

Dose-dependent activation of Syk and SHIP1 by LynA and LynB at steady state creates a threshold for macrophage signaling in the absence of receptor engagement

S. Erandika Senevirathne, Carter Sellner, Silvia Toledo Ramos, Tanya S. Freedman

The paper shows that LynA and LynB expression levels determine steady-state phosphorylation of Syk and SHIP1, limiting macrophage signaling without microbial stimulation.

DOI 10.64898/2026.02.25.708040

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 16, 2025

Steady-state phosphorylation of SHIP1 by Lyn restricts macrophage activation in the absence of a phagocytic synapse

S. Erandika Senevirathne, William K. Kanagy, Richard T. Cattley…·Tanya S. Freedman

The paper shows that Lyn maintains steady-state phosphorylation of SHIP1, balancing Erk and Akt signaling in macrophages, and that phagocytic synapse formation bypasses this requirement.

1 citation

mouseproteomics

𝕏 PostBluesky