Jibran Younis Khokhar

This study examines how different cannabis THC:CBD compositions affect oligodendrocyte progenitor cells in mice after acute vapor inhalation, finding morphological and mitochondrial changes similar to early differentiation.

This study examines the effects of chronic cannabis vapour exposure and withdrawal on behavioural networks in rats, finding significant reorganization of behavioural dynamics.

The paper develops a transient marmoset model of myofascial temporomandibular disorder using nerve growth factor injections, showing mechanical hypersensitivity and circadian changes without jaw dysfunction.

This paper introduces an open-source restraint system for awake rat fMRI that eliminates anesthesia, reducing stress and motion artifacts while enabling high-quality imaging and behavioral integration.

This paper conducts GWAS on cannabis use frequency and lifetime use, identifies genetic loci, and shows genetic correlations with other traits and diseases.

This study investigates the polygenic relationship between cannabis use and schizophrenia using data from the All of Us Research Program, finding independent associations between polygenic scores for cannabis use disorder and schizophrenia.

This study shows CBD increases HPA axis activity in male mice and reduces anxiety in female mice with low HPA function, with sex-specific effects on behavior and stress responses.

This study investigates genetic correlations and causal relationships between schizophrenia, cannabis use disorder, and tobacco smoking across African and European ancestries, identifying pleiotropic loci and convergent genetic effects.

This study compares GWAS results of coffee intake from 23andMe and UK Biobank, finding discrepancies in genetic correlations with health traits and highlighting cultural differences in gene-cohort influences.

This study investigates the neural and behavioral effects of cannabis poisoning in rats, finding sex-dependent changes in THC levels and gamma power suppression linked to cognitive impairments.

This study examines how adolescent exposure to alcohol and vapourized nicotine affects reward and cognition in adult male and female rats, finding sex-specific behavioural differences.

This study examines how cannabis vapour with THC or balanced THC:CBD affects oscillatory activity in a schizophrenia model, finding THC suppresses activity while CBD balances its effects.

This study investigates the effects of chronic chemogenetic manipulation of ventral pallidum neurons in rats on an obesogenic diet, finding unexpected weight gain despite hypothesized reductions in food consumption.

The paper uses LFP oscillations from the ventral striatum to predict feeding behavior in rats, finding an optimal balance between model complexity and performance.

The paper uses machine learning to predict deep brain stimulation outcomes in a rat binge eating model based on ventral striatal oscillations, finding better prediction accuracy than chance.