T. Reinert

Single-cell quantification of the iron-neuromelanin balance in dopaminergic neurons across the lifespan

The paper quantifies iron and neuromelanin in dopaminergic neurons across chimpanzee lifespan, finding stable iron-to-neuromelanin ratios and no evidence of saturation or increased toxicity with age.

Human short association fibers are thinner and less myelinated than long fibers

The paper analyzes human white matter fibers to compare thickness and myelination between long and short fibers, finding shorter fibers are thinner and less myelinated but have similar g-ratio.

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

The paper challenges the view that axonal degeneration in MS results from immune-mediated damage by proposing that myelin itself increases axonal degeneration risk under inflammatory conditions.

Toward an early diagnostic marker of Parkinson's: measuring iron in dopaminergic neurons with MR relaxometry

The paper links MRI relaxation rate in substantia nigra to iron concentration in dopaminergic neurons, enabling early Parkinson's disease detection.