April Pruitt

The paper evaluates estradiol's effects on ASD/NDD genes using human neurons and zebrafish, finding both convergent transcriptomic effects and gene-specific cellular and behavioral rescue.

This study develops a long-lived zebrafish primary neuron culture protocol and uses it to show that scn1lab mutants exhibit hyperproliferation of non-neuronal cells.

This study identifies convergent biological pathways in mature neurons affected by neurodevelopmental disorder risk genes and shows drug candidates can ameliorate behavioral phenotypes.