Author

Meilín Fernández García

Yale UniversityORCID 0000-0002-8745-9775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Kristen BrennandiD· 4 shared Laura M. HuckinsiD· 4 shared Annabel SeniD· 3 shared Kayla G. TownsleyiD· 3 shared April PruittiD· 2 shared Carina SeahiD· 2 shared Ellen J. HoffmaniD· 2 shared Grace Dossou· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetics

Kristen BrennandORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Convergent and divergent phenotypic impacts of estradiol on neurodevelopmental disorder risk genes

April Pruitt, Liang Yang, Seoyeon Lee, Novin Balafkan, Shilin Gao, Carina Seah, Yi Dai, Elizabeth Davidson, Suha Khan, Annabel Sen, Jenny Liu, Isabel Wood, Gang Xu, Xiayuan Huang, Marina Carlson, , Kristen Brennand

The paper evaluates estradiol's effects on ASD/NDD genes using human neurons and zebrafish, finding both convergent transcriptomic effects and gene-specific cellular and behavioral rescue.

bioRxiv · Sep 19, 2026 · PreprintGenomics

Dynamic neuro-immune regulation of psychiatric risk loci in human neurons

Kayla G. Townsley, S. H. Lee, Sarah Williams, Sam Cartwright, Sophie Cohen, Annabel Sen, Meng Jia, Hannah E. Young, Lee Dobbyn, Michael Deans, Meilín Fernández García, Laura M. Huckins, Kristen Brennand

The paper investigates how maternal and fetal immune activation interacts with genetic risk profiles to influence neuronal regulatory activity and psychiatric traits.

Nature Communications · Aug 27, 2026Peer-reviewedGenetics

Mechanical stretch disrupts calcium dynamics and redistributes Piezo1 in human astrocytes

Shahrzad Shiravi, Akash Chakka, Xi Xiao, Meilín Fernández García, Alexandra Yufa, Angela Mitevska, Carina Seah, H Gao, Laura M. Huckins, Kristen Brennand, John D. Finan

This study uses a 2D stretch injury model to show that mechanical stretch disrupts calcium dynamics, mitochondrial function, and Piezo1 distribution in human astrocytes, with temporary effects at moderate injury severity.

Annals of Biomedical Engineering · Feb 5, 2026Peer-reviewedNeuroscience

Dynamic convergence of neurodevelopmental disorder risk genes across neurodevelopment

Meilín Fernández García, Kayla G. Townsley, April Pruitt, Elizabeth Davidson, Novin Balafkan, Jonathan Warrell, Tzu-Chieh Huang, Alfred Kibowen, Zhiyuan Chu, Yi Dai, Sarah E. Fitzpatrick, Ran Meng, Annabel Sen, Sophie Cohen, Olivia Livoti, , Kristen Brennand

This study identifies convergent biological pathways in mature neurons affected by neurodevelopmental disorder risk genes and shows drug candidates can ameliorate behavioral phenotypes.

bioRxiv · Aug 23, 2024 · PreprintGenetics