Leon Y. Cai

Generalized brain-state modeling with KenazLBM

KenazLBM is a model that characterizes and predicts brain states from raw iEEG data, generalizing across subjects with heterogeneous recording channels.

Brain-state modeling using electroencephalography: Application to adaptive closed-loop neuromodulation for epilepsy

This paper introduces BrainState, a self-supervised method to model complex brain states from EEG data, applied to epilepsy patients to capture pre-seizure states and neuromodulation effects.

White matter tract microstructure, macrostructure, and associated cortical gray matter morphology across the lifespan

The paper characterizes lifespan changes in white matter microstructure, macrostructure, and associated cortical morphology using large datasets, finding unique developmental and aging trajectories across brain pathways.

Whole-brain, gray and white matter time-locked functional signal changes with simple tasks and model-free analysis

The paper investigates BOLD signal changes in both white and gray matter using model-free analysis and simple tasks, finding time-locked activations across the whole brain.

Short superficial white matter and aging: a longitudinal multi-site study of 1,293 subjects and 2,711 sessions

The paper analyzes longitudinal MRI data from 1,293 subjects to study age-related changes in superficial white matter microstructure and U-fiber volume and length.

Superficial white matter across the lifespan: volume, thickness, change, and relationship with cortical features

This study quantifies superficial white matter volume and thickness across the lifespan using large datasets, finding unique age-related changes and relationships with cortical features.

Multi-channel deep learning with intracranial neurostimulation can localize seizure onset zones in humans

This paper develops a deep learning model to classify seizure onset zones using cortico-cortical evoked potentials from intracranial neurostimulation recordings.

Aging and white matter microstructure and macrostructure: a longitudinal multi-site diffusion MRI study of 1,184 participants

This study analyzes diffusion MRI data from 1184 participants to quantify age-related changes in white matter microstructure and macrostructure, finding that macrostructural features show more heterogeneous age-related decline.

Fiber tractography bundle segmentation depends on scanner effects, vendor effects, acquisition resolution, diffusion sampling scheme, diffusion sensitization, and bundle segmentation workflow

This study evaluates how scanner, vendor, resolution, diffusion scheme, and segmentation workflow variations affect diffusion tractography bundle segmentation results.