Catherine A. Lebel

The Canadian Pediatric Imaging Platform (C-PIP) Reference Sample: Neuroimaging Protocol and Cross-site Validation for Harmonized Multimodal Pediatric Imaging

The paper describes the development of a harmonized multisite MRI protocol for pediatric brain imaging and validates its cross-site consistency.

Spatiotemporal Variation in White-Matter Development Across Early Childhood

This study examines spatiotemporal patterns of white matter development in children using longitudinal diffusion imaging data, revealing distinct developmental axes within tracts.

Longitudinal Associations Between Screen Time, Brain Development, and Language Outcomes in Early Childhood

This study examines how screen time at age two relates to language outcomes and brain development at ages two and three, finding negative associations between screen time and brain volumes.

Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development

The paper examines the longitudinal relationship between phonological decoding ability and fiber density in the left arcuate fasciculus across reading development.

Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero

This study identifies altered brain metabolites in children with prenatal alcohol exposure linked to executive functioning and excitability.

White matter tract microstructure, macrostructure, and associated cortical gray matter morphology across the lifespan

The paper characterizes lifespan changes in white matter microstructure, macrostructure, and associated cortical morphology using large datasets, finding unique developmental and aging trajectories across brain pathways.

Changes in brain metabolite levels across childhood

The paper examines age-related changes in brain metabolite levels in children aged 2-11 years using MRS, finding age-related increases and decreases in several key metabolites in specific brain regions.

Hypothalamic vasopressin sex differentiation is established during embryonic neurogenesis

The paper shows that hypothalamic vasopressin neurons are sexually dimorphic during embryonic neurogenesis, with exposure to bisphenol A causing masculinization in female brains.

Multimodal brain features at preschool age and the relationship with pre-reading measures one year later: an exploratory study

This study examines how brain features in preschool children relate to pre-reading skills one year later using multimodal imaging and behavioral assessments.

Association between breastfeeding during infancy and white matter microstructure in early childhood

This study finds that breastfeeding exclusivity and duration are associated with white matter microstructure in children, with sex-specific effects on fractional anisotropy.

White Matter Alterations in Young Children with Prenatal Alcohol Exposure

This study identifies white matter microstructural differences in young children with prenatal alcohol exposure compared to controls using diffusion tensor imaging.

Multimodal principal component analysis to identify major features of white matter structure and links to reading

The paper uses multimodal PCA on white matter imaging data to identify structural features linked to reading and age, finding no direct reading skill associations but age-related changes in microstructure.

Maturation and interhemispheric asymmetry in neurite density and orientation dispersion in early childhood

This study uses NODDI to examine age-related changes in neurite density and orientation dispersion in children's white matter, finding increases in density but no change in dispersion.

Early childhood development of white matter fiber density and morphology

The paper quantifies white matter development in early childhood using fixel-based analysis and finds greater morphological than microstructural changes.

Cerebral Blood Flow Increases Across Early Childhood

This study maps cerebral blood flow (CBF) development in children aged 2-7 years, finding a continuous increase in CBF across brain regions without gender differences.

Examining the relationship between prenatal depression, amygdala-prefrontal structural connectivity and behaviour in preschool children

This study examines how prenatal depression relates to brain structure and behavior in preschool children, finding that altered structural connectivity mediates the effect of maternal depressive symptoms on externalizing behavior in males.

Tractography Reproducibility Challenge with Empirical Data (TraCED): The 2017 ISMRM Diffusion Study Group Challenge

The paper evaluates tractography reproducibility using empirical data from a single healthy volunteer scanned on two scanners, finding high consistency among top algorithms but variability due to tract volume containment.

Global and regional white matter development in early childhood

This study characterizes white matter development in early childhood, showing increases in fractional anisotropy and decreases in mean diffusivity, with sex differences and significant changes in occipital and limbic connections.

Time efficient preparation methods for MRI brain scanning in awake young children and factors associated with success

The paper describes a time-efficient preparation method for MRI scans in young children and finds that cognitive abilities predict success better than mock scanner training.

Diffusion MRI of white matter microstructure development in childhood and adolescence: Methods, challenges and progress

This paper reviews diffusion MRI methods for studying white matter development in childhood and adolescence, highlighting challenges and recent progress in understanding brain maturation.

Brain white matter structure and language ability in preschool-aged children

The paper examines the relationship between preschool-aged children's language skills and brain white matter structure, finding structural markers for language difficulties as early as 3 years of age.