Molecular BiologyNature CommunicationsPeer-reviewed
FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells
Ke Cong, Nathan J. MacGilvary, Silviana Lee…·Sharon B. Cantor
The paper investigates how FANCJ helicase affects PARP1 activity during DNA replication in BRCA1 deficient cells, revealing its role in PARPi efficacy and resistance.
23 citationstop 4%