Author

Sharon B. Cantor

University of Massachusetts Chan Medical SchoolORCID 0000-0003-2944-6156Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrew G. Li· 1 shared Arne Nedergaard KousholtiD· 1 shared Brenda C. Chan· 1 shared David M. LivingstoniD· 1 shared Elizabeth C. Murphy· 1 shared Jennifer A. CalvoiD· 1 shared Joan S. BruggeiD· 1 shared Ke CongiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew G. Li

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMar 23, 2024

FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells

Ke Cong, Nathan J. MacGilvary, Silviana Lee…·Sharon B. Cantor

The paper investigates how FANCJ helicase affects PARP1 activity during DNA replication in BRCA1 deficient cells, revealing its role in PARPi efficacy and resistance.

23 citationstop 4%

humanDNA methylation

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Molecular BiologybioRxivPreprintNov 2, 2022

The BRCA1 isoform, BRCA1-IRIS, operates independently of the full-length BRCA1 in the Fanconi anemia pathway

Andrew G. Li, Brenda C. Chan, Elizabeth C. Murphy…·David M. Livingston

This study identifies BRCA1-IRIS as a critical isoform for ICL repair, distinct from BRCA1-p220, by interacting with FANCD2 and promoting its ubiquitylation.

DOI 10.1101/2022.11.02.514969

humanexperimental assay

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