Chakkarai Sathyaseelan

The paper introduces a new antibody capture method to accurately capture G4 structures in human cells and shows that G4 formation is constrained by sequence properties and nuclear environment.

The paper analyzes global SARS-CoV-2 proteome variation to identify mutational hotspots in drug and vaccine targets, finding that some mutations are co-occurring and others are geographically prevalent.

The paper uses an extreme gradient boosting decision-tree algorithm to predict nucleic acid secondary structures from circular dichroism spectra with high accuracy.