Author

Lydia L. Shook

Harvard UniversityORCID 0000-0002-5859-8610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Andrea G. EdlowiD· 3 shared Evan A. BordtiD· 3 shared Alexis M. CeasrineiD· 2 shared Benjamin A. DevliniD· 2 shared Donna K. SlonimiD· 2 shared Rebecca BatorskyiD· 2 shared Roy H. PerlisiD· 2 shared Sezen KışlaliD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersDevelopmental Biology

Andrea G. EdlowORCID

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3 papers

Recent·Most cited

Developmental BiologyCell ReportsPeer-reviewedJun 1, 2024

Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity

Rebecca Batorsky, Alexis M. Ceasrine, Lydia L. Shook…·Andrea G. Edlow

The paper shows that Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity, suggesting Hofbauer cells as a noninvasive biomarker for fetal microglial programming.

38 citationstop 3%

mousehuman

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Developmental BiologybioRxivPreprintDec 3, 2021

Single cell profiling of Hofbauer cells and fetal brain microglia reveals shared programs and functions

Alexis M. Ceasrine, Rebecca Batorsky, Lydia L. Shook…·Andrea G. Edlow

The paper uses single-cell RNA sequencing to compare fetal brain microglia and Hofbauer cells, revealing shared transcriptional programs and sex-specific differences.

10 citations

mousehuman

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Developmental BiologybioRxivPreprintApr 1, 2021

Placental expression of ACE2 and TMPRSS2 in maternal SARS-CoV-2 infection: are placental defenses mediated by fetal sex?

Lydia L. Shook, Evan A. Bordt, Marie-Charlotte Meinsohn…·Andrea G. Edlow

The paper examines placental ACE2 and TMPRSS2 expression in relation to maternal SARS-CoV-2 infection and fetal sex, finding sexually dimorphic effects on TMPRSS2 but not ACE2.

DOI 10.1101/2021.04.01.438089

humanbulk RNA-seq

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