Jessica E. Messier

The paper shows that deleting Neuroligin-2 from specific neurons disrupts synaptic excitation-inhibition balance, causing lethality, while deleting it from both neuron types allows survival.

This study shows that Stxbp1 haploinsufficiency in mice causes cognitive, psychiatric, and motor impairments and cortical hyperexcitability, similar to STXBP1 encephalopathy in humans.

The paper shows that light-gated chloride channels can have excitatory effects in presynaptic terminals and introduces a targeting motif to improve their inhibitory function in somatodendritic regions.