ImmunologybioRxivPreprint
DNA-PKcs governs LAT-dependent signaling in CD4+ and CD8+ T cells
Randall R Rainwater, Ana Clara P. Azevedo‐Pouly, Zachary J. Waldrip…·Marie Burdine
This study shows DNA-PKcs interacts with LAT at the immune synapse, phosphorylates specific serines, and is essential for T cell function in tumor control and graft rejection.
DOI 10.1101/2025.03.06.641745