Author

Randall R Rainwater

Arkansas Children's Research InstituteORCID 0009-0002-0840-1784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Clara P. Azevedo‐PoulyiD· 2 shared Marie Burdine· 2 shared Nicholas A. CallaisiD· 2 shared Aaron J. StoreyiD· 1 shared Belle H. Hicks· 1 shared Brian S. KossiD· 1 shared John Schaller· 1 shared Lyle Burdine· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Ana Clara P. Azevedo‐PoulyORCID

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2 papers

Recent·Most cited

Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression

Nicholas A. Callais, Shawn Welch, Randall R Rainwater, John Schaller, Shuoqiu Deng, Ana Clara P. Azevedo‐Pouly, Marie Burdine, Lyle Burdine

An acellular spleen perfusion platform enables serial multiomic sampling to identify steroid-responsive transcriptional programs, validate SOCS3 protein induction, and nominate a non-transcriptional immunosuppressive axis.

bioRxiv · May 19, 2026 · PreprintBioengineering

DNA-PKcs governs LAT-dependent signaling in CD4+ and CD8+ T cells

Randall R Rainwater, Ana Clara P. Azevedo‐Pouly, Zachary J. Waldrip, Belle H. Hicks, Nicholas A. Callais, Brian S. Koss, Aaron J. Storey, Lyle J. Burdine, Marie Burdine

This study shows DNA-PKcs interacts with LAT at the immune synapse, phosphorylates specific serines, and is essential for T cell function in tumor control and graft rejection.

bioRxiv · Mar 6, 2025 · PreprintImmunology